Uprising

As Coulson, Mack and Fitz attempt to track down and neutralize a rogue group looking to end Inhuman Registration worldwide, Simmons and Dr. Radcliffe only have hours to save May before she succumbs forever to her mysterious illness.

Guest Stars

Natalia Cordova-BuckleyElena 'Yo-Yo' Rodriguez / Slingshot

Gabriel LunaRobbie Reyes / Ghost Rider

Jason O'MaraJeffrey Mace / The Patriot

Lorenzo James HenrieGabriel Reyes

Parminder NagraSenator Ellen Nadeer

Patrick CavanaughAgent Burrows

Alexander WraithAgent Anderson

Mallory JansenAida

Jen SungChen

Valery M. OrtizMaria

Derek HughesThe Amazing Mertz

Preston FlaggDarryl

Stephanie Maura SanchezLeticia

Dale PavinskiBriggs

Ricky SaenzPistol Punk

Devon LibranSlugger Punk

Michael Cory DavisAgitator

Adriana Diaz ChapaHostage

Aaron GaffeyMystery Figure

Jake GreenTerrified Driver